5 March 2024

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Nasal drops brain stroke

Nasal drops show remarkable results in stroke recovery, research finds

Researchers have discovered that nasal drops containing a specific chemical can help mice recover from the negative biological repercussions of a stroke.

Because of this achievement, researchers now have higher hopes for the treatment’s eventual use in humans.

According to a press statement from the University of Gothenburg, the work currently published in the Journal of Clinical Investigation is a multicenter study in which researchers tested an experimental stroke treatment on mice in parallel with Nasal drops. The investigation was carried out in partnership with Czech Academy of Sciences experts.

The scientists observed that by giving mice a chemical Nasal drops, the complement peptide C3a, via nasal drops, they recovered motor function sooner and better after stroke than mice given a placebo.

These findings support and extend a prior study conducted at the University of Gothenburg, and the current study design adds to its legitimacy.

Nasal Drops Positive Effects

“We see the same positive effects in experiments done in Sweden and Germany, which makes the results much more robust,” said Marcela Pekna, Professor of Neuroimmunology at Sahlgrenska Academy, University of Gothenburg, who conducted the research.

“There is no need to race against the clock with this method.” If the medication is employed in clinical practise, it might be given to all stroke patients, including those who arrive at the hospital too late for thrombolysis or thrombectomy. “Those who have residual disabilities after the clot is removed may benefit from this treatment as well,” Pekna said.

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biological effects of a stroke 

A stroke occurs when the blood supply to a part of the brain is interrupted or reduced, leading to damage to brain cells due to lack of oxygen and nutrients. The biological effects of a stroke can vary depending on the severity of the stroke, the location of the affected area in the brain, and the individual’s overall health. Here are some common biological effects of a stroke:

  1. Neurological deficits 

Strokes often result in neurological deficits, which can manifest as weakness or paralysis on one side of the body (hemiparesis or hemiplegia Nasal drops). This occurs because the part of the brain responsible for controlling movement is affected. Other deficits may include difficulty with coordination, balance, or fine motor skills.

  1. Speech and language difficulties 

Depending on the location of the stroke, individuals may experience difficulty speaking or understanding speech. This condition is known as aphasia. Aphasia can affect a person’s ability to express thoughts, find words, or comprehend written or spoken language.

3. Cognitive impairment                                                                                              Strokes can lead to cognitive impairments such as memory loss, difficulty with attention and concentration, reduced problem-solving abilities, and changes in judgment and decision-making.

Nasal drops brain stroke

These cognitive deficits can affect a person’s ability to perform daily tasks and may require rehabilitation and support.

  1. Sensory disturbances

 Strokes can cause sensory disturbances, such as numbness or tingling, on one side of the body. Individuals may also experience changes in vision, including blurred or double vision, loss of peripheral vision, or difficulty with depth perception.

  1. Emotional and psychological changes

 Strokes can have a significant impact on a person’s emotional well-being. Depression, anxiety, irritability, and mood swings are common after a stroke. Some individuals may also experience emotional lability, where they have exaggerated or uncontrollable emotional responses.

  1. Fatigue and sleep disturbances 

Many stroke survivors experience fatigue and may require additional rest and sleep. Sleep disturbances, such as insomnia or sleep apnea, can also occur following a stroke, further contributing to fatigue.

  1. Swallowing difficulties 

Strokes can affect the muscles involved in swallowing, leading to dysphagia (difficulty swallowing). This can increase the risk of aspiration (food or liquids entering the airway) and may require dietary modifications and swallowing therapy.

  1. Changes in bladder and bowel function

Strokes can disrupt the normal control of bladder and bowel function, leading to urinary or fecal incontinence or difficulty emptying the bladder or bowels.

It’s important to note that the extent and duration of these effects can vary widely among individuals, and many stroke survivors undergo rehabilitation and therapy to regain function and improve their quality of life. Prompt medical attention and appropriate rehabilitation measures are crucial for maximizing recovery after a stroke. Let’s see how much time does Nasal drops research will take on humans.